Bromethalin - Accidentally killing pets since 1985

  • bromine- and fluorine-containing diphenylamine-derived neurotoxic rodenticide
  • developed in 1985 in response to the rise of strains of rodents who were resistant to the effects of anticoagulant rodenticides (e.g. warfarin)
  • causes rodents to give up the ghost by uncoupling oxidative phosphorylation in the mitochondria of neurons, which depletes their cellular ATP stores and ultimately leads to axon damage and the disruption of normal neural communications producing paralysis, convulsions, and ultimately death
  • has been known to poison cats or dogs that eat rodents that have been killed by it (as well as those that simply eliminate the middleman by eating the rat bait itself)
  • no specific antidote, and while osmotic diuretics and corticosteroids may do something beneficial, the best way to deal with a poisoning is to eliminate it from the gastrointestinal tract (induce vomiting/give activated charcoal)
Pasquale-Styles MA et al. Fatal bromethalin poisoning. J Forensic Sci. 2006 Sep;51(5):1154-7.

4 chemically inspired comments:

Toaster Sunshine said...

It never ceases to amaze me the kinds of chemicals a dog can get into and chew on.
My dog recently got into Avermectin B (emetic + activated charcoal) and, just today, a suspension of neomycin sulfate, polymixin B sulfate, and bacitracin (milk).

Do you perchance know what kind of chemicals are in Fatal+? I know it's some kind of anesthetic used in overdose to sac lab animals, but that is the extent of my knowledge.

Anonymous said...

this is a cheap imitation from adoptamicrobe.blogspot.com

it is clear since this page has been built before hers. what a moron you are, u see a person whose infatuated with bacteria and viruses and u go ahead and create a site titled drugs and poisons.

pathetic! be oringal man.

CND said...

Aww, my very own Internet troll!

The Mayor said...

Aw, don't worry - her's is just a pedestrian, Japanime version of yours.
PS - I need more haters over at The Skip-Raid. Send 'em over!