Loperamide - Because no one likes pooping emergencies

• trade names include Lopex, Imodium, and Dimor
• analogue of meperidine (a synthetic opioid) used to deal with diarrhea / suppress the squirts / prevent the poops / revert the runs / thwart the trots / squash the skitters
• acts on opioid receptors in the gastrointestinal tract to decrease fluid secretion and peristalsis
• also used to treat fecal incontinence (loss of the ability to restrain from just pooping whenever there is poop to be pooped) since it increases anal sphincter tone
• is metabolized in the intestinal wall, so very little of it is absorbed into the systemic circulation and delivered to the rest of the body
  
• is mostly charged at physiological pH, so it cannot cross readily into the brain, meaning that even though it is an opioid like morphine or heroin it cannot get you stoned and has no potential for causing dependence