tag:blogger.com,1999:blog-37623912.post8483650422820462560..comments2007-02-25T09:50:41.118-05:00Chrishttp://www.blogger.com/profile/05349466286549537039[email protected]Blogger4125tag:blogger.com,1999:blog-37623912.post-64369580840555050042007-02-25T09:50:00.000-05:002007-02-25T09:50:00.000-05:00Woot!1 I have a scoop!1 *grin*<BR/><BR/>I know part of the danger with antiemetics-plus-ototoxic drugs is that they mask the nausea and vomiting that often show up. But i do know that they specifically mask the ototoxicity, too. I'm not sure why they could keep the brain from noticing the cranial nerve damage. Hrm. I'll try to see what i can find.Ursahttp://www.creature57.com/blog/[email protected]tag:blogger.com,1999:blog-37623912.post-21003370966459698782007-02-25T02:13:00.000-05:002007-02-25T02:13:00.000-05:00and i always thought BBB stood for<BR/>bullshit baffles brains.<BR/>Applicable in this instance also.<BR/>but this is not a snide comment, just an afterthoughtalekhttp://www.blogger.com/profile/04775602542292718767[email protected]tag:blogger.com,1999:blog-37623912.post-48308178426912301012007-02-24T17:56:00.000-05:002007-02-24T17:56:00.000-05:00Hey, thanks for the inside scoop. Now I've got to figure out exactly why antiemetics mask otoxocity. It always surprises me what strange and wonderful side effects a drug can produce.<BR/><BR/>I sort of rushed this post, so I plan on revamping it a bit and adding a couple more drugs at some point in the future.CNDhttp://www.blogger.com/profile/05349466286549537039[email protected]tag:blogger.com,1999:blog-37623912.post-53335270802609147352007-02-24T14:43:00.000-05:002007-02-24T14:43:00.000-05:00Hmm. Interesting. <BR/><BR/>We use Reglan (metoclopramide) on patients who've had abdominal surgery of some sort, i believe, in combination with docusate and/or sennokot to get their bowels moving again. I hadn't realized it was an antiemetic, although that makes sense--the faster your stomach empties, the less chance it has to decide that it doesn't want its contents anymore.<BR/><BR/>We tend to use Phenergan (promethazine) as our drug of choice for nausea. (I think there's another drug we use, but it's not coming to me at the moment. Regardless, we use Phenergan a lot.) <BR/><BR/>One interesting thing to be aware of with antiemetics is that they can mask the ototoxic effects of drugs like vancomycin and gentomycin, as well as aspirin. (Prentice Hall Nurse's Drug Guide, 2005 ed.)Ursahttp://www.creature57.com/blog/[email protected]