tag:blogger.com,1999:blog-37623912.post655469492545746806..comments2010-05-30T01:09:20.697-04:00Chrishttp://www.blogger.com/profile/05349466286549537039noreply@blogger.comBlogger6125tag:blogger.com,1999:blog-37623912.post-81632645652601554122008-10-18T09:39:00.000-04:002008-10-18T09:39:00.000-04:00Ibogaine can completely cure opiate addiction while completely suppressing withdrawal symptoms (anyone who kicks and goes through Hell didn't have to).<BR/><BR/> There are clinics operating in NYC and Tijuana doing this right now (it's a Schedule I controlled substance however, so it's kind of low profile). It's also been shown to work for addictive behavior in general, with success reported for opiates, stimulants (cocaine, meth), nicotine, and alcohol.The Village Idiotnoreply@blogger.comtag:blogger.com,1999:blog-37623912.post-31460535700259338702008-07-07T23:03:00.000-04:002008-07-07T23:03:00.000-04:00just wanted to know .. are there any major pharmaceutical companies which market a medication with lobeline as its active ingridient ? I'm in india and i would love to give up smoking.I tried cold turkey once but it didnt work out all too well ( wonder why ? )prosaicalhttp://www.blogger.com/profile/16832668623031328970noreply@blogger.comtag:blogger.com,1999:blog-37623912.post-47336564875905127622008-05-10T15:17:00.000-04:002008-05-10T15:17:00.000-04:00Yeah, compliance and withdrawal are definitely going to be problems if it's just straight-up antagonizing opioid and nicotinic receptors.Chrishttp://www.blogger.com/profile/05349466286549537039noreply@blogger.comtag:blogger.com,1999:blog-37623912.post-11359464917649554052008-05-09T20:48:00.000-04:002008-05-09T20:48:00.000-04:00It's an interesting idea, using lobeline as an "anti-addictive." But if it is really blocking mu-opioid and NicACh receptors, what kind of compliance are you gonna get? Like naltrexone with alcoholics and opiate addicts, people don't want to take something that is gonna be a buzz kill. <BR/><BR/>Further, taking this drug while under the effects of opiates or nicotine could cause some unpleasant withdrawal symptoms, no?The Lil'est Naturisthttp://www.blogger.com/profile/03666824355018596756noreply@blogger.comtag:blogger.com,1999:blog-37623912.post-25910978652126769372008-04-23T23:10:00.000-04:002008-04-23T23:10:00.000-04:00I found a couple of papers on methods for chiral separation of lobeline, but nothing on the activity of the individual enantiomers.Chrishttp://www.blogger.com/profile/05349466286549537039noreply@blogger.comtag:blogger.com,1999:blog-37623912.post-51420856114495789872008-04-21T21:41:00.000-04:002008-04-21T21:41:00.000-04:00It is a racemic compound. Has it been resolved? Is one perticular enantiomer more active than the other?pmgbpmgb.wordpress.comnoreply@blogger.com